I’m surprised… usually there are “manager” cards that can open all doors (or almost all doors).
You will definitely want to use the Dangerous NFC app first to disable lock bytes and protect the capability container (page 03). It will also set a password and protect the configuration bytes at the end of the tag, but those will definitely not be used by the hotel key system… so protect your tag with Dangerous NFC and you will always be able to overwrite whatever the hotel key system puts on your xNT.