Not necessarily… the term “mifare” is now almost as meaningless as “vehicle”… it can mean many different things. In short, if the system those readers are attached to only care about UID, and support the “later” mifare UIDs that are 7 bytes (not the old NUIDs that are only 4), then possibly the xNT could work with such a system. Typically the best way to figure out if it’s possible is to test it, and hopefully do that testing in collaboration with the card system operator or manager.
https://forum.dangerousthings.com/t/chip-compatibility-with-systems-and-devices