The anti🚫-derailment🚃 & thread🧵 hijacking🔫 thread🧵 ⁉

[Atilla]

I wanted to avoid the low hanging fruit… Mr Garrison regarding the US presidency.

@Pilgrimsmaster

i thought I should move mine out of respect.

I’m glad to see the process of implantation =)

[Eriequiet]

Just a spitball idea, sure I’m not the first to ask it

What would happen if you coated something transdermal with a bio bond agent?

Would that help prevent the normal infections that people reference since the body could seal better to it?

[Eyeux]

@Eriequiet

What would happen if you coated something transdermal with a bio bond agent?

Probably you would either end up with a pinch-like feeling when you move, depending on the region, and no much more.

Or, more likely, most biobond materials tend to become flaky and break down a bit if they meet trauma. or age. Not something I would want on me…

Also the better seal you can get is when your inner sticky bits get in touch with more of your inner sticky bits. So anything in between will most likely be worst than nothing in between.

But could help for the very few who can experience 30cm migration…

[Atilla]

Long story short: NO
You want the piercing to be as smooth as possible.
You want the tissue to heal around it not into it.
Also the hole cleans itself when it heals, you want those juices to come out, hence the importance of smoothness.

Edit: Speaking from experience. I tried it as a teen… I know, right!

Not the best way to get pus squirting if ya know what I mean…

[Eriequiet]

@Atilla

You want the tissue to heal around it not into it.

Weird

You would think you want it to seal, to let you skin function as a proper barrier, keeping stuff out

@Atilla

you want those juices to come out

I assume it’s not as simple, but don’t bodily juices belong in the body? , waste fluids already have existing systems for removal

Wouldn’t the funky juice you want to drain, not be generated if there was no means for microbes to get by into your skin?

[Atilla]

Oh, it seals up, but the bio-material is generally porous, and the rigid surface irritates the cells. If the object is smooth as butter the healing is much quicker.

Yes, the body gets rid of whatever juices it doesn’t need. However if you insert a foreign object in it that is the least considered normal.
Imagine a splinter. The body wants to encapsulate and eject that, rather then digest it.

If you are interested in piercings I warmly recommend to look up JC’s channel on youtube.
He was doing videos for years about this topic. He covered pretty much whatever could be covered regarding to piercings. google:pangeapiercing
P.S.: If you see him pass my very-best wishes!!

[Eriequiet]

@Atilla

If you are interested in piercings

Not really, just looking at it as a tool for future implant interactionif we can make them actually last and not reject or infect

Imagine a SD card in Amal’s goop, with a female usb C as a transdermal

[Atilla]

Interesting topic.
AFAIR there was a snippet about this: if it’s easier to sterilise a polished surface, or how rigid does a surface need to be to prevent growth.

When I was a kid we had iodine-tincture ampules in 1st aid kits.
The alcohol evaporates quickly and as the iodine crystallises it makes the surface hostile for microbes to live on. Same theory goes with photofunctionalization.

[Atilla]

We should have started defining bio-bond and bio-safe first.
Luckily this is the off-topic.
However, it would be interesting to start a topic about it.

Back to the practical aspect:
An USB port poking out from the skin: Yes, that would likely to be coated with material that binds with tissue. BUT not the stem that goes trhough the skin, only the anchoring bit.

[Eriequiet]

@Atilla

We should have started defining bio-bond and bio-safe first.
Luckily this is the off-topic.

I suppose we should start at the beginning,

I made the assumption that transdermals eventually fail because of microbial stuff getting past the skin

If this is the case, we need to seal better

If this isn’t the case I’m in the wrong road

I was just thinking that the skin actually attaching to the object that’s perforating it, would for a better seal that simple constriction and allow the skin to function like normal

[Atilla]

I was thinking about similar things before I started looking into it deeply.
You don’t need to seal it off once it’s healed.

[Eriequiet]

@Atilla

You don’t need to seal it off once it’s healed.

Then why does stuff reject or fail?

[anon7067117]

Now, I’m no expert, but there are a couple of points:
-Transdernals present excellent surfaces for skin dwelling bacteria to bond to (for example S. epidermidis looooves infecting inplants/catheters because it is excellent at forming biofilms which are really difficult to kill

• it doesnt so much bond with the body as it “sits” in a “skin pocket” with a bigger inside where the anchor sits and smaller opening - the way the transdermal is attached is through holes in the anchor where the skin can regrow back together, it isnt actually bonded directly - now, these are small, and as you can imagine, quite easy to rip. It would probably need just a tug or snagging on clothing or something to create an ooen wound. And the opening where the transdermal ‘head’ pokes out is an excellent ingress point for all sorts of nasties that could infect that wound. And as the infection is partially hidden hidden in the pocket, any antimicrobial agents (antibiotic creams etc) have a hard time getting to the wound and biofilms are also very resistant to them

Im sorry if i am confusing ts 4 am
@Coma has more experience with transdermals so she could probably tell you more

[Eriequiet]

@anon7067117

And the opening where the transdermal ‘head’ pokes out is an excellent ingress point for all sorts of nasties that could infect that wound.

So how do we move beyond a pocket, and turn the skin into a bulkhead

[amal]

the problem has been kicked around by the medical device industry for ages… ports and other medical devices that have wires, tubes, sensors, etc. that go through the skin all have this problem. the reason nothing has made progress comes down to how cells grow and how the layers of skin work. too tired to brain dump at the moment but basically its just not viable unless we come up with a gene edit that changes how those skin cells around the transdermal device actually grow and produce “skin”.

there are coatings like hydroxyapatite and tricalcium phosphate that can help with bone bonding … but bone building osteoblasts are not skin cells… and the body mod community has one particular snake oil salesman trying to sell transdermals with hydroxyapatite coatings claiming it will help the skin close up… but this does not work.

[ODaily]

Learning from nature then.

How does the bone protrude from a deer’s skull to form antlers without having this problem?

[amal]

@ODaily

How does the bone protrude from a deer’s skull to form antlers without having this problem?

its not bone really… its more like your fingernail and has special cells that grow matrix with the skin

edit: well for deer i guess its closer to bone… but anyway it’s built into the DNA on how to grow that … so yeah we could do some gene edits

[ODaily]

makes me think of those Deer Lord pics.

[Eriequiet]

@amal

too tired to brain dump at the moment but basically its just not viable unless we come up with a gene edit

That’s fair

I knew it was an ongoing thing, just musing on the fact we have stuff that makes flesh adhere, and things that don’t work well because flesh doesn’t adhere to them

Seemed too easy, but was curious on the issues at play

[Atilla]

Almost like a is biting into it"s tali.
If it goes through the surface it imposes the hazard of infection.
If it’s wireless it needs power source for extended function.

I’m waiting for Neuralink to sort this out.
The convinced me.

…As we know I am easily convinced, feel free to disagree.